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Drug manufacturers continue to deny wrongdoing, but patients deserve accountability and compensation for the harm they have suffered

Transfusion may improve oxygen delivery and dilute out the number of sickle cells, and thus is beneficial in certain conditions ( Currently, the only two curative treatments of SCD are hematopoietic stem cell transplantation (HSCT) and Lyfgenia, another recently FDA-approved gene therapy that modifies patients stem cells to produce normal hemoglobin (Figure 1)

Social media plays an outsized role in this region, where influencer endorsements are the primary catalyst for the "No Makeup" trend, encouraging consumers to invest in ingestibles that create a naturally radiant "inner glow" finish

Dilokthornsakul et al 15 reported that most adverse events were gastrointestinal tract symptoms or skin reactions

One of these studies also failed to identify any change in anxiety-like behavior 162 , while two further studies employing exendin-4 observed an anxiogenic effect following acute administration 158,169