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When you wake up, your stomach is empty, which is the ideal environment for many supplements to be processed without interference from food

Am J Physiol Gastrointest Liver Physiol 296(3):G461G475 Szarka LA, Camilleri M, Vella A, Burton D, Baxter K, Simonson J et al (2008) A stable isotope breath test with a standard meal for abnormal gastric emptying of solids in the clinic and in research

Distilled water is perfectly safe to drink, but because of the lack of minerals, it might taste flat in comparison to regular tap water