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There are many unknowns, including dose-response in humans, interactions with other fertility treatments, and differences at various stages of conception including gametogenesis, implantation, and gestation
Frequency is typically once daily for general effects or twice daily for acute conditions, often taken in morning for mental clarity (though timings relevance is unproven)
Folic acid and B12 are generally safe when taken in recommended amounts
PubMed Blonde, L., Umpierrez, G.E., Reddy, S.S., McGill, J.B., Berga, S.L., Bush, M., et al
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