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Worms were manually homogenized on ice using VWR Pellet Mixer Adaptor

For isolated CTR, a classic incision was used, whereas a modified Brunner curvilinear incision was chosen for patients undergoing both CTR and Guyon canal release

Large cardiovascular outcome trials involving over 60,000 patients found no statistically significant increase in pancreatitis rates with GLP-1 agonists versus placebo

doi: 10.1186/s12929-023-00899-2 198 ShellySLukinovaNBambinaSBermanACherryS

Notably, the STEP (Semaglutide Treatment Effect in People with obesity) trials, which specifically examined body composition, demonstrated substantial weight loss compared with placebo (NCT03548935) [53], and reductions in fat mass and visceral adipose tissue were accompanied by decreases in lean mass, although the proportion of lean mass relative to total body mass increased (NCT04074161) [54]