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Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis

10.1111/j.1399-3054.2006.00785.x 39 GomezL.VanackerH.BuchnerP.NoctorG.FoyerC

doi: 10.3390/molecules29051125 79 Montero-LenLCruz-GregorioAHernndez-CruzEYSciuttoEFragosoGPedraza-ChaverriJ

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They're often used together because they work through complementary mechanismsCJC-1295 provides sustained growth hormone release over days, while ipamorelin produces a more immediate effect