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Overall, the extent to which GLP-1RAs cross the bloodbrain barrier remains uncertain in pre-clinical studies 4 , and further discrepancies are expected in translating these data from animals to humans

However, other causes of menstrual changes are completely unrelated to GLP-1s, such as perimenopause, other medications, or another health issue

The cagrilintide side effect profile adds some considerations beyond standard GLP-1 effects

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doi:10.36849/JDD.6550 Samantha Ouellette BA, Giulia Frias BA, Radhika Shah MD PharmD, Mahin Alamgir MD, Cindy Wassef MD Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Somerset, NJ Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic agents that work by inducing insulin secretion and inhibiting release of glucagon in a glucose-dependent manner