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10.1016/j.jsams.2017.03.015 195 MarstonK

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Transcriptomic analysis identifies key METTL3-regulated pathways disrupted by Cd, highlighting m 6 A-dependent epigenetic regulation as a central mechanism in cadmium-induced hepatotoxicity (130)

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The functional role of TGF-/Smad signaling in liver fibrosis has been demonstrated by the finding that Smad3 downregulation ameliorated dimethylnitrosamine-induced hepatic fibrosis (Latella et al., 2009)