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And I havent had massive results, but enough for people to notice, which is great. Gay has witnessed, however, that people treat her differently even with just minor weight loss

This is the brain to testicle stimulation pathway, he says Dr

An 8-week double-blind randomized placebo-controlled trial in 62 patients with PWS demonstrated an improvement of hyperphagiaevaluated as behavior and severity scores by Dykens Hyperphagia Questionnaireafter Topiramate group versus placebo group, with no effects on BMI [95]

Last reviewed: July 18, 2026 Last updated: July 18, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations