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These metabolites also affect epigenetic and cellular mechanisms involved in tumor suppression and metabolic health, positioning SCFAs as key mediators in probiotic-induced health benefits (175177)

For instance, in renal fibrosis, AST mainly exerts its effects by modulating cellular signaling pathways and immune cell infiltration, while in pulmonary fibrosis, its mechanisms primarily focus on regulating fibroblast behavior through lncRNA and mitochondrial signaling pathways

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