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Downstream transcription factors showed dramatic upregulation: c-Fos by 4.99-fold, c-Jun by 7.05-fold, and Egr-1 by 3.70-fold

HOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICY Our findings are consistent with the adjudged less harmful effects of HTP compared with traditional cigarettes, which could have reduced the perceived necessity for SCT among cigarette users following widespread adoption of HTP in the Japanese market

Designed for precision research, DSIP is primarily investigated for its unique ability to cross the blood-brain barrier and modulate rhythmic biological processes without the heavy sedative effects associated with traditional pharmacological agents

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When reading the results (m 2 ) columns, be sure to note the value of each calibrated line on the scale at the intersection point