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Secondary signals across both trials reduced knee osteoarthritis pain, fewer obstructive sleep apnea events, improvements in triglycerides, blood pressure, LDL, and hsCRP suggest systemic metabolic remodeling rather than simple caloric suppression

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The Journal of clinical pediatric dentistry

After cleaning duplicate entries, disproportionality measures (reporting odds ratio (ROR), proportional reporting ratio (PRR), and relative reporting ratio (RRR)) were calculated, with Evans criteria applied to assess signal significance

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