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Pain, mild swelling, crusting and erosions are some of the commonly reported side-effects of PDT

Fratta Pasini et al., 2021)

Specifically, HMW-HA maintains tissue hydration and suppresses pro-inflammatory signaling by attenuating TLR4/NF-B activation, while concurrently enhancing IL-10 and TGF- expression through CD44 receptor engagement on macrophages and fibroblasts [7]

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