While our nested casecontrol design, PSM analyses, dynamic PDC-based exposure assessment, and subgroup analyses help mitigate these concerns, they cannot fully eliminate them
Using themselves as subjects and RIA, they demonstrated that people experience higher insulin levels when they eat sugar than when it is injected into their bloodstream (McIntyre, Holdsworth, Turner)
However, in some special circumstances or at special time points, treatment with GH may also increase DNA damage or decrease DNA damage repair, such as exposing GH to the GHD Lewis dwarf rats and Snell dwarf mice in prepubertal results in decreased DNA repair by leading to dysregulation of DNA damage proteins (Podlutsky et al., 2017)
But when the effect is too pronounced, nausea follows
10.1158/1541-7786.MCR-21-0702 59 FernandoS.WallaceE