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AOD-9604 Research Protocols & Administration Dosing in Published Research Research investigations have employed diverse AOD-9604 doses across species and administration routes: Rodent studies: 250-500 mcg/kg orally or intraperitoneally was most common for obesity research Rabbit models: 0.25 mg per joint for osteoarthritis studies (intra-articular injection) Pig pharmacokinetic studies: 1.5 mg/kg IV and 2 mg/kg oral for metabolism characterization Human clinical trials: Oral doses of 0.25-10 mg daily

Quick Answer: Semaglutide typically lowers blood pressure rather than raising it, with clinical trials showing systolic reductions of 38 mmHg primarily through weight loss and metabolic improvements

If the randomization value was missing, the screening value (if available) was used

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