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Furthermore, BRCA1 can suppress IGF-1R promoter activity in androgen receptor-negative prostate cancer cell lines but enhance IGF-1R expression at the transcriptional level in androgen receptor-positive prostate cancer cell lines (203)

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In the JAMA Ophthalmology study, researchers included records of more than 510,000 patients in a national database, about half who were prescribed GLP-1 medication and half who were not

Although numerous therapies exist including topical corticosteroids, vitamin D analogs, systemic immunosuppressants, and biologics targeting specific cytokines their use is often limited by high cost, adverse effects, immunosuppression, or loss of efficacy over time

Evidence suggests that higher protein intake during weight loss may help preserve lean mass