The recent positive topline results from Eli Lilly and Company 's ATTAIN-MAINTAIN trial for orforglipron, however, signal a potential paradigm shift
These studies illustrate broad investigative interest, but they also underscore that effects vary by model and mechanism
It may play a role in maintaining and modulating neuronal functions and supportive nutrients that may help modulate brain excitability and inflammation
Funding This research was funded by the National Key Research and Development Programs of China, grant number 2022YFC2603801, the Maternal and Child Health Project of Jiangsu Province (F201717), the Doctor Project of Affiliated Hospital of Jiangsu University (jdfyrc2019003), and Clinical and Virology Study of 2019-ncov Infection in Patients with Moderate to Severe Psoriasis (Jdfyxgzx005). Publishers note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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