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7.2 Relaxin-3 and the behavioral dimension of metabolic disease Relaxin-3, a member of the relaxin peptide family predominantly expressed in the nucleus incertus, signals through the RXFP3 receptor and exerts pronounced effects on feeding behavior, arousal, stress responsiveness, and cognitive processing in animal models ( At first glance, this profile appears incompatible with obesity therapy

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References: Krinsky DL, LaValle JB, Hawkins EB, et al

Side effects are generally mild injection site irritation, temporary water retention, or vivid dreams (common with GH secretagogues)