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Later, Gerson used this therapy to treat diseases like tuberculosis and cancer

Research models suggest it engages the metabolic activity associated with this region while lacking the amino acid sequence responsible for the receptor-mediated, insulin-antagonizing effects of the intact hormone

In recent years, the role of GPX3 in oxidative stress has been reported, for example: GPX3 can inhibit the expression of HIF1- by regulating ROS, thereby inhibiting the growth of melanoma cells (Yi et al., 2019)

This results in the recruitment of immune cells and the release of pro-inflammatory cytokines, which in turn influence keratinocyte and fibroblast activity 43 , 47

However, there is a lack of understanding of the relationship between specific and non-specific Se metabolism (Tobe and Mihara, 2018)