Those Nerdy Girls Link to Original Substack Post
Emerging evidence suggests that GLP1 therapy can: Reduce hepatic fat content, as shown in MRI-PDFF studies Lower markers of liver inflammation and fibrosis Improve insulin sensitivity and metabolic control Although most trials focus on obese or diabetic populations, livercentric endpoints are increasingly evaluated, and benefits appear to extend beyond weight loss alone
Sakurai M, Weber P, Wolff G, Wieder A, Szendroedi J, Herzig S, Ustunel E, B
This non-canonical role of Smad5 promotes the acidification of insulin secretory vesicles that ultimately promotes insulin processing and secretion
These compounds may damage cellular DNA and increase the expression of genes associated with retinal pigment epithelial cell aging