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NTZ at 100 mg/kg failed to alleviate hepatic histopathology scoring significantly (Figures 8BD), which is in alignment with the features displayed in photomicrographs of H&E-stained liver sections where moderate hepatoportal and sinusoidal congestion, moderate periportal inflammatory infiltrate, and moderate hepatocytes necrosis were found

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Tirzepatide produced even larger average weight reductions in the SURMOUNT-1 trial, depending on dose

Alkhedhairi SA, Aba Alkhayl FF, Ismail AD, Rozendaal A, German M, MacLean B, et al

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