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Primary candidates include adults with type 2 diabetes and obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with weight-related comorbidities who have not achieved adequate glycemic control or weight loss goals with metformin monotherapy

They are running an uncontrolled experiment on their own tissue

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tolerance is significantly reduced on semaglutide Skipping meals causes fatigue, dizziness, and worsens cravings later Large portions triggers nausea within 3060 minutes Lying down after eating worsens reflux significantly Inadequate hydration worsens nausea, constipation, fatigue, and headache Rapid dose escalation discuss with your prescriber if symptoms are severe When Side Effects Mean You Should Stop and Call Your Doctor Most side effects are tolerable and resolve

Patients looking for weight loss treatment can complete an online consultation to see whether a licensed treatment may be suitable