Together with other aspects of the PWS phenotype including, in many cases, a reduced sensitivity to pain, hyperphagia results in life-threatening obesity and life-shortening complications for some people with PWS
As the cost of these medications comes down and more people recognize the long-term benefits of obesity treatment, we may start to see insurance companies changing their approach
Because it acts on the central nervous system, clonidine can also affect other functions, such as pain perception and withdrawal symptoms, in some cases
Their use is currently contraindicated for patients with atypical anorexia nervosa, bulimia nervosa, or subthreshold bulimia nervosa, as GLP-1RAs could worsen the restrictive eating behaviors common in these conditions
A gym membership alone does not count