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After the trial results are released, authorities such as the Medicines and Healthcare products Regulatory Agency (MHRA) and the National Institute for Health and Care Excellence (NICE) will assess whether to approve the treatment for UK use

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By regulating the Nrf2/HO-1 pathway, A5 improves the activity of SOD and GPX and the level of glutathione, reduces the levels of iron deposition, 4-HNE and MDA, thereby improving the ferroptosis of neurons induced by TBI

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