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We tested the modified Dihexa against 200 M neomycin and observed no protection, suggesting that the current form of Dihexa has a high specificity for providing protection, likely via its specific interaction with native HGF (Figure 7)

What should researchers do if unexpected FOXO4-DRI side effects are observed

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The first column of Table 5 shows the average percent change in the levels of six plasma metabolites in 42 Down patients compared to controls (taken from [13])