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The pharmacokinetics and tissue distribution of sinomenine in rats and its protein binding ability in vitro

A slight increase was noted in active GLP-1 levels in the portal blood 120 min after the administration of TO

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In diabetischen Ratten, die bekanntlich eine stark verzoegerte Wundheilung aufweisen, zeigte die PIC-Behandlung erhoehte Glutathion- und Ascorbinsaeurespiegel, verbesserte Epithelialisierung sowie eine gesteigerte Aktivierung von Fibroblasten und Mastzellen im Wundgebiet

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