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In a highdose semaglutide trial (7.2 mg weekly), participants lost about 20.7% of body weight in 72 weeks, with a substantial portion achieving up to 25% weight loss

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In order to further explore the specific mechanism of HMSeBA regulating intestinal ER stress signal, we established an ERS model of IPEC-J2 cells in vitro

Overall, the study underscores the functional relevance of the extrinsic apoptotic pathway in RBC senescence and clearance

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