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Graphical Abstract Similar content being viewed by others Introduction Osteoporosis is a common metabolic skeletal disease characterized by low bone mineral density and degeneration of bone tissue microarchitecture that affects specific categories of people, especially the elderly and postmenopausal women (Xu et al

These tools enable a systematic investigation of how metformin modulates pathways linked to metabolic dysfunction, chronic viral infections, and AD, uncovering mechanistic insights that remain unexplored in experimental and clinical studies

In trials, participants on 2.4 mg weekly lost on average about 15% of body weight over 68 weeks [2]

Sowa says

This titration approach helps minimise gastrointestinal side effects, which are the most commonly reported adverse reactions