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the data collection period for each measure varies depending on measure specifications that set minimum case requirements to ensure individual measure reliability and meet the requirements of CMS quality programs, as detailed in each program's respective rules as well as on Hospital Compare or its successor website (85 FR 86202)

Reduced inflammation, improved biomechanics, and metabolic reprogramming likely act in concert, opening perspectives that go beyond mere mechanical off-loading of the joint

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The data were collected using the MassLynx v4.1 software (Waters Corp.) and the ratio of the peak area of analyte to the IS was analyzed by TraverseMS (Reifycs Inc., Tokyo, Japan)

This approach aligns with the goals of a systematic review into a novel research area, where the primary aim is to gather and describe existing knowledge rather than to rigorously assess study quality or synthesize outcomes quantitatively