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Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a chi

The treatment reduces melanin production and lightens pigmentation

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In terms of safety, the optimization of the delivery system resulted in a significant reduction of irritation in the compounded formulation, with the main adverse effects identified in the trials being transient erythema (5.2%) and dry skin (2.1%) (Palliyage et al., 2021)

The amount of color in both normal skin and various lesions is determined by several factors: the density of melanocytes, the amount of melanin produced per melanocyte, and the transfer rate of the melanized melanosomes to the 30 or so keratinocytes that surround each melanocyte