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Complications of modern, intrastromal keratopigmentation include corneal perforation, bacterial infection, allergic or toxic reaction to pigment, migration of pigment, and functional complications like visual field limitation and light sensitivity

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According to the American Academy of Dermatology (AAD), melanin stops regrowing after 7 to 15 full hair cycles, leading to a gradual loss of hair color

Cosmetic formulations, being pre-mixed liquids or creams, might have different, often less stringent, storage recommendations for shelf-life

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