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Common signs include: Fatigue and weakness Numbness or tingling in the hands and feet Difficulty walking or balance problems Mood changes, such as depression or anxiety Cognitive difficulties, including memory loss or confusion If not treated, a B12 deficiency can cause serious problems
However, the in vivo results obtained from studies [16, 40] are contradictory, underscoring the necessity for further investigation into specific mechanisms that extend beyond empirical observations
The homogenate was centrifuged at 15,000 g at 4 C for 20 min, and the supernatant was used for measuring the activity of CAT, GR, APX, DHAR, and MDHAR (Zhang and Kirkham 1996)
Pathogenesis of alcoholic liver disease: role of oxidative metabolism