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Semaglutide is a GLP-1 receptor agonist already approved separately as Ozempic, Wegovy, and Rybelsus depending on formulation and indication

[DOI] [PMC free article] [PubMed] [Google Scholar] 127.Johnston E.A., Petersen K.S., Beasley J.M., Krussig T., Mitchell D.C., Van Horn L.V., Weiss R., Kris-Etherton P.M

Key distinctions include: Origin : GLP-1 is naturally occurring

Thus, GLP-1 and GLP-1RAs have a beneficial effect on neurogenesis, potentially having translational significance, since these compounds can have a positive effect in various mental disorders characterized by defects in neurogenesis (including depressive disorders and neurocognitive disorders)

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