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DHAR (EC 2.5.1.1.8) activity was assayed chromatically according to the method described by 1 cm 1

However, the course of treatment should be at least 6 months to obtain good results, which may have side effects, including skin atrophy, telangiectasia (spider vein, dilation of blood vessels), and acneiform eruptions (in this case, it is advisable to switch to topical immunomodulators)

Moreover, the responders had significantly higher levels of total glutathione ( p = 0.01) and reduced glutathione ( p = 0.01) at baseline compared to the non-responders (Figure 4) within this group

Gannon MC, Nuttall JA, Nuttall FQ