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One of the interesting factors in ferroptosis regulation in SCD is through heme oxygenase 1 (Hmox1), which cleaves heme to form biliverdin and thus plays a protective role in vascular function 42,43,44,45

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The analysis, conducted by researchers from the University of Oxford and supported by the National Institute for Health Research (NIHR) Oxford Health Biomedical Research Centre and the Medical Research Council, revealed that taking the drug, a popular medication for type II diabetes, had no increased risk of adverse neurological or psychiatric outcomes compared to other antidiabetic medications, challenging recent concerns about the drug's safety

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