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In the first few weeks, weight changes may be minimal, but this is normal

Strategies to Break Through Semaglutide Weight Loss Plateaus When you hit a semaglutide plateau, the first strategy is dose optimization

HAARLEM study baseline characteristics

These indication-specific regimens are relevant for mechanistic interpretation, because higher dose exposure and differing baseline metabolic states in obesity-focused cohorts may yield larger weight-loss responses and distinct endpoint profiles compared with T2DM trials, where glycemic control and diabetes-related outcomes represent primary targets

This review keeps the lens on Wegovy and semaglutide, the pathway that fills the order, and the biology a prescription cannot read