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4 Conclusion and outlook This article reviews the molecular mechanisms of ferroptosis-induced osteoporosis, summarizes the signaling pathways through which ferroptosis affects bone metabolism, and focuses on the three-dimensional regulatory network of iron metabolism disorder, lipid peroxidation and bone homeostasis imbalance

Preclinical animal studies, in vitro mechanistic investigations, and human clinical studies were eligible

2017;12(6):e0179538

During the procedure, stem cells are often collected from the patients bone marrow or fat tissue, processed, and then injected into the affected area

Pappas G, Akritidis N, Bosilkovski M, Tsianos E