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A cosmetic chemist writing in Happi magazine confirmed this concern, noting that while copper is strongly bound to the peptide, EDTA's affinity for copper is even stronger

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doi: 10.1038/nn.2778 278 TristB

Finally, our findings are consistent with the significantly increased AMPK expression in pre-infusion CD19-CAR T cell products of patients in complete response compared to non- or partial responders as well as decreased functionality of CD19-CAR T cells upon AMPK inhibition 23

Smith, Anthony R