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While many individuals experience positive results, GLP-1 receptor agonists are not ideal for those with certain medical conditions, such as pancreatitis, thyroid issues, or a personal/family history of medullary thyroid carcinoma

The dosing schedule also affects outcomes, since these medications are most effective when taken regularly and as prescribed

Gastroenterology 86(6):15921610 Moake MM, Presley BC, Hill JG et al (2022) Point-of-care ultrasound to assess gastric content in pediatric emergency department procedural sedation patients

Liraglutide could reduce monthly migraine days Liraglutide, a glucagon-like peptide-1 receptor (GLP-1R) agonist used to treat diabetes, appears to reduce monthly migraine days by more than half, researchers reported on June 20, 2025 at the annual European Academy of Neurology (EAN) Congress 25