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3- Changes in Insulin and Glucose Homeostasis Affecting Nerve Function: As GLP-1 receptor agonists alter glucose metabolism, there is potential for downstream effects on neuronal excitability and peripheral nerve function

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This selectivity represents a fundamental difference from not only full-length growth hormone but also growth hormone secretagogues and analogs like tesamorelin, which increase endogenous growth hormone and subsequently elevate IGF-1

Whether the heptapeptide fragment fully recapitulates the parent proteins effects in vivo is unresolved

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