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If youre planning to become pregnant, discuss stopping the medication with your provider beforehand

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For Botox, side effects may include bruising, pain at the injection site, and headaches

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Using injections sporadically (e.g., twice one week, skipping two weeks, then resuming) prevents the cumulative hepatic remodeling that produces measurable fat loss

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Discuss with your clinician about adjusting your GLP-1 dosing schedule if constipation is severe Consider prescription medications for persistent constipation that doesnt respond to other measures When to seek medical advice Contact your healthcare provider if you experience: No bowel movement for more than 4-5 days Severe abdominal pain or distension Blood in the stool Constipation alternating with diarrhoea Unexplained weight loss or fatigue Constipation that doesnt improve with self-management strategies Long-term outlook For most patients, constipation either resolves as the body adjusts to GLP-1 therapy or can be effectively managed with dietary and lifestyle modifications

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The evidence is now clear: living with overweight or obesity increases the risk of multiple cancers, including bowel, endometrial, post-menopausal breast, kidney, liver, pancreatic, gallbladder, ovarian, gastric cardia, oesophageal adenocarcinoma, thyroid, meningioma, and multiple myeloma

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