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After adjusting for age, sex, WC, BMI, alcohol, smoking, diabetes, hypertension, dyslipidemia and metabolic syndrome, insulin resistance, transaminases, and Hba1c, the association remained statistically significant with LSM (B=0.952

Akiyama H, MD, PhD, Zhao R, BS, Rahhal A, BS, Nishida Y, MD, PhD, Ayoub E, PhD, Ostermann LB, BS, Andreeff M , MD, PhD, Ishizawa J, MD, PhD

LeBoffMSChouSHMurataEMDonlonCMCookNRMoraSet al

Increased melanin production lead to epidermal hyper-pigmentation like dark scarring, age spots, and overall uneven epidermal tone

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