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Holst Lange pointed to the additive contribution of cagrilintide as evidence that the amylin mechanism delivers meaningful benefit beyond GLP-1 monotherapy, and noted that higher-dose CagriSema development is ongoing

The study is registered at PROSPERO with ID CRD420250655809

In October 2019, the United States Food and Drug Administration (FDA) approved MT1 under the brand name Scenesse for increasing sunlight tolerance and alleviating pain from ultraviolet (UV) light exposure in patients with erythropoietic protoporphyria (EPP) [4]

However, its potential benefits in emergency situations, such as severe hypoglycemia or diabetic ketoacidosis, have garnered significant attention in recent years

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