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The most noticeable differences between the unmatched GLP-1 RA group and the DPP-4i group were sex (43.1% vs
S3F), these results point to a major contribution of GCGR in the eWAT (lipolysis)-pancreas (insulin secretion)-liver (FAO/ketogenesis/FGF21) interactome as an early event in G49 action that drives the metabolic flexibility described in this study
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