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The target dose is usually 300 mg per day , though some may increase to 400 mg per day under medical supervision

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The human gut microbiota: Metabolism and perspective in obesity

Participants treated with subcutaneous semaglutide 2.4 mg were initiated on a dose of 0.25 mg once weekly and the dose was escalated every 4 weeks to 0.5 mg, 1.0 mg and 1.7 mg, until the target dose of 2.4 mg was reached at week 16