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While non-dopaminergic agents thus have a long history in the treatment of PD motor symptoms, there have only been few new drug approvals in recent years

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COVID-19/phase-III: thrombocytopenia Acute COVID-19 due to severe iron toxicity from oxidized iron could modulate several systemic pathways of coagulation cascade and cause thromboembolism 99

In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]