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A 2024 research review showed that creatine supplementation improved memory and processing time but did not indicate significant improvements to overall cognitive function

Tirzepatide, a dual GLP-1 and GIP receptor agonist, showed even greater weight reduction in the SURMOUNT trials, with some participants achieving 22% body weight loss

Triple agonists take this strategy further by targeting GLP-1R, GIPR, and the glucagon receptor (GCGR), aiming to regulate multiple complementary metabolic pathways

Currently, only four brand-name GLP-1s are approved for use in pediatric and adolescent populations

doi: 10.1016/j.freeradbiomed.2018.05.074 38 BaiskhanovaDSchaferH