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This might include one or more of the following medications: dulaglutide (Trulicity) exenatide (Bydureon) liraglutide (Victoza, Saxenda) lixisenatide (Adlyxine) semaglutide (Ozempic, Rybelsus, Wegovy) These are GLP-1 receptor agonists that the FDA has approved for conditions such as: managing type 2 diabetes obesity fatty liver disease improving cardiovascular health However, more research is needed to determine whether they may be effective in treating OSA

Ten of the 11 PFS-related pathways were associated with microbial diversity

Options like inulin, fructooligosaccharides (FOS), and galactooligosaccharides (GOS) not only help with constipation but may also support a healthier gut microbiome, which can be beneficial when your digestive system is adjusting to GLP-1 medications

DAMPs also impact Kupffer cells, activating the nucleotide-binding oligomerization domain-like receptor (NLR) Family, Pyrin Domain-Containing 3 protein (NLRP3), a type of inflammasome leading to IL-1 secretion and inflammation, and pyroptosis, releasing more DAMPs and perpetuating a destructive cycle (Peiseler et al., 2022)

The demographics of the study population also present a limitation