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Why it matters: GLP-1 drug costs to public and commercial insurance are soaring

Overview of current and emerging GLP-1 receptor agonists

4 However, GLP-1 receptor agonists and gut-derived GLP-1 do not cross the bloodbrain barrier and cannot access GLP-1 receptors in the brain parenchyma, which can only be accessed by brain (pre-proglucagon neuron) derived GLP-1

Studies have investigated DSIP's effects on gonadotropin release, growth hormone secretion, and other pituitary hormone dynamics in research models, positioning it as a compound of interest in neuroendocrine axis research

The injection is absorbed much more efficiently, so more of the dose reaches your bloodstream