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Moreover, a recent randomized crossover study in healthy women demonstrated that prolonged mild sleep restriction markedly increased endothelial oxidative stress without activating compensatory antioxidant responses, due to reduced expression of DCUN1D3 gene, a regulator of the Nrf2-mediated antioxidant pathway, thereby suggesting a mechanistic link between insufficient sleep and vascular oxidative injury 78

This metabolic profile is driven by the overexpression of numerous genes and proteins involved in glucose uptake and glycolysis

We evaluated adipogenic and angiogenic activities by immunofluorescence and observed a higher number of intact perilipin-positive mature adipocytes in the GSH-treated group than in the control group

two-way ANOVA

Unregulated IV glutathione may cause life-threatening systemic inflammatory response syndrome (SIRS)