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Individual components of the apoptotic machinery involved in regulation of ER stress-mediated cell death include Bax, Bak, Bim, or PUMA (p53 upregulated modulator of apoptosis), as well as the transcription factor CHOP (C/EBP homologous protein)-dependent pathway [89]

Dosimetry of 177 Lu-PSMA-617 in metastatic castration-resistant prostate cancer: correlations between pretherapeutic imaging and whole-body tumor dosimetry with treatment outcomes

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